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1

CD45 in human physiology and clinical medicine

Rheinländer, Andreas, Schraven, Burkhart, Bommhardt, Ursula

Journal:

Immunology Letters

Year:

2018

Language:

english

File:

PDF, 661 KB

english, 2018

2

Retarded thymic involution and massive germinal center formation in NF-ATp-deficient mice

Kai Schuh, Burkhard Kneitz, Jörg Heyer, Ursula Bommhardt, Eriks Jankevics, Friederike Berberich-Siebelt, Klaus Pfeffer, Hans Konrad Müller-Hermelink, Anneliese Schimpl, Edgar Serfling

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 698 KB

english, 1998

3

Heterogeneity in P-glycoprotein (multidrug resistance) activity among murine peripheral T cells: Correlation with surface phenotype and effector function

Ursula Bommhardt, Jean-Charles Cerottini, H. Robson MacDonald

Journal:

European Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 878 KB

english, 1994

4

Developmentally regulated expression of P-glycoprotein (multidrug resistance) activity in mouse thymocytes

H. Robson MacDonald, Ursula Bommhardt, Jean-Charles Cerottini

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 379 KB

english, 1995

5

Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus

Ursula Bommhardt, Michael S. Cole, J. Yun Tso, Rose Zamoyska

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 1.48 MB

english, 1997

6

γc cytokines provide multiple homeostatic signals to naive CD4+ T cells

Guillemette X. Masse, Erwan Corcuff, Hélène Decaluwe, Ursula Bommhardt, Olivier Lantz, Jan Buer, James P. Di Santo

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 467 KB

english, 2007

7

Molecular and cellular mechanisms of T Cell development

U. Bommhardt, M. Beyer, T. Hünig, H.M. Reichardt

Journal:

Cellular and Molecular Life Sciences

Year:

2004

Language:

english

File:

PDF, 380 KB

english, 2004

8

CD3ε ligation in the absence of co-receptor-mediated lck recruitment promotes CD8 differentiation

M.A. Basson, U. Bommhardt, M.S. Cole, J. Yun-Tso, R. Zamoyska

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 167 KB

english, 1997

9

Molecular requirements for lineage commitment in the thymus – antibody-mediated receptor engagements reveal a central role for lck in lineage decisions

M. Albert Basson, Ursula Bommhardt, P. Joe Mee, Victor L. J. Tybulewicz, Rose Zamoyska

Journal:

Immunological Reviews

Year:

1998

Language:

english

File:

PDF, 7.36 MB

english, 1998

10

10.1038/89106

Avota, Elita, Avots, Andris, Niewiesk, Stefan, Kane, Lawrence P., Bommhardt, Ursula, ter Meulen, Volker, Schneider-Schaulies, Sibylle

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 547 KB

english, 2001

11

An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development

Patra, Amiya K, Avots, Andris, Zahedi, René P, Schüler, Thomas, Sickmann, Albert, Bommhardt, Ursula, Serfling, Edgar

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.81 MB

english, 2012

12

Constitutive Akt1 signals attenuate B-cell receptor signaling and proliferation, but enhance B-cell migration and effector function

Pierau, Mandy, Na, Shin-Young, Simma, Narasimhulu, Lowinus, Theresa, Marx, Alexander, Schraven, Burkhart, Bommhardt, Ursula H.

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

13

Immunosuppression by N-Methyl-D-Aspartate Receptor Antagonists Is Mediated through Inhibition of Kv1.3 and KCa3.1 Channels in T Cells

Kahlfuss, S., Simma, N., Mankiewicz, J., Bose, T., Lowinus, T., Klein-Hessling, S., Sprengel, R., Schraven, B., Heine, M., Bommhardt, U.

Journal:

Molecular and Cellular Biology

Year:

2014

Language:

english

File:

PDF, 3.13 MB

english, 2014

14

How Many Thymocytes Audition for Selection?

Merkenschlager, M., Graf, D., Lovatt, M., Bommhardt, U., Zamoyska, R., Fisher, A. G.

Journal:

Journal of Experimental Medicine

Year:

1997

Language:

english

File:

PDF, 209 KB

english, 1997

15

196

Patra, Amiya K., Avots, Andris, Zahedi, René P., Schüler, Thomas, Sickmann, Albert, Bommhardt, Ursula, Serfling, Edgar

Journal:

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

16

Critical role of thymocyte-derived brain-derived neurotrophic factor in T cell maturation

Lühder, Fred, Linker, Ralf, Lee, De-hyung, Reichardt, Holger, Bommhardt, Ursula, Gold, Ralf, Flügel, Alexander

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

17

NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells

Simma, Narasimhulu, Bose, Tanima, Kahlfuß, Sascha, Mankiewicz, Judith, Lowinus, Theresa, Lühder, Fred, Schüler, Thomas, Schraven, Burkhart, Heine, Martin, Bommhardt, Ursula

Journal:

Cell Communication and Signaling

Year:

2014

Language:

english

File:

PDF, 5.07 MB

english, 2014

18

TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells

Bekeredjian-Ding, I., Doster, A., Schiller, M., Heyder, P., Lorenz, H.-M., Schraven, B., Bommhardt, U., Heeg, K.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 588 KB

english, 2008

19

Protein Kinase B/Akt Signals Impair Th17 Differentiation and Support Natural Regulatory T Cell Function and Induced Regulatory T Cell Formation

Pierau, M., Engelmann, S., Reinhold, D., Lapp, T., Schraven, B., Bommhardt, U. H.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 2.20 MB

english, 2009

20

PKB Rescues Calcineurin/NFAT-Induced Arrest of Rag Expression and Pre-T Cell Differentiation

Patra, A. K., Drewes, T., Engelmann, S., Chuvpilo, S., Kishi, H., Hunig, T., Serfling, E., Bommhardt, U. H.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 712 KB

english, 2006

21

Active Protein Kinase B Regulates TCR Responsiveness by Modulating Cytoplasmic-Nuclear Localization of NFAT and NF- B Proteins

Patra, A. K., Na, S.-Y., Bommhardt, U.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 948 KB

english, 2004

22

Akt Decreases Lymphocyte Apoptosis and Improves Survival in Sepsis

Bommhardt, U., Chang, K. C., Swanson, P. E., Wagner, T. H., Tinsley, K. W., Karl, I. E., Hotchkiss, R. S.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 731 KB

english, 2004

23

CD3 Ligation on Immature Thymocytes Generates Antagonist-like Signals Appropriate for CD8 Lineage Commitment, Independently of T Cell Receptor Specificity

Albert Basson, M., Bommhardt, U., Cole, M. S., Tso, J. Y., Zamoyska, R.

Journal:

Journal of Experimental Medicine

Year:

1998

Language:

english

File:

PDF, 352 KB

english, 1998

24

Constitutively Active Protein Kinase B Enhances Lck and Erk Activities and Influences Thymocyte Selection and Activation

Na, S.-Y., Patra, A., Scheuring, Y., Marx, A., Tolaini, M., Kioussis, D., Hemmings, B., Hunig, T., Bommhardt, U.

Journal:

The Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 725 KB

english, 2003

25

Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation.

Na, S.- Y., Patra, A., Scheuring, Y., Marx, A., Tolaini, M., Kioussis, D., Hemmings, B., Hunig, T., Bommhardt, U.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 106 KB

english, 2006

26

Quantitative and qualitative differences in IL-2 and IL-4 expression in primary and secondary T cell stimulation

Bommhardt, Ursula, Sadlack, Benjamin, Schimpl, Anneliese

Journal:

International Immunology

Year:

1992

Language:

english

File:

PDF, 5.82 MB

english, 1992

27

A Logical Model Provides Insights into T Cell Receptor Signaling

Saez-Rodriguez, Julio, Simeoni, Luca, Lindquist, Jonathan A., Hemenway, Rebecca, Bommhardt, Ursula, Arndt, Boerge, Haus, Utz-Uwe, Weismantel, Robert, Gilles, Ernst D., Klamt, Steffen, Schraven, Burkha

Journal:

PLoS Computational Biology

Year:

2007

Language:

english

File:

PDF, 751 KB

english, 2007

28

Insulin and insulin-like growth factor-1 can modulate the phosphoinositide-3-kinase/Akt/FoxO1 pathway in SZ95 sebocytes in vitro

Mirdamadi, Yasaman, Thielitz, Anja, Wiede, Antje, Goihl, Alexander, Papakonstantinou, Eleni, Hartig, Roland, Zouboulis, Christos C., Reinhold, Dirk, Simeoni, Luca, Bommhardt, Ursula, Quist, Sven, Goll

Journal:

Molecular and Cellular Endocrinology

Year:

2015

Language:

english

File:

PDF, 5.13 MB

english, 2015

29

Hedgehog signaling in T-cell development: A non-redundant role for Gli1

Bommhardt, Ursula

Journal:

Year:

2010

Language:

english

File:

PDF, 520 KB

english, 2010

30

Thymocyte-derived BDNF influences T-cell maturation at the DN3/DN4 transition stage

Linker, Ralf A., Lee, De-Hyung, Flach, Anne-Christine, Litke, Tanja, van den Brandt, Jens, Reichardt, Holger M., Lingner, Thomas, Bommhardt, Ursula, Sendtner, Michael, Gold, Ralf, Flügel, Alexander, L

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

31

MEK Activity Regulates Negative Selection of Immature CD4+CD8+ Thymocytes

Bommhardt, U., Scheuring, Y., Bickel, C., Zamoyska, R., Hunig, T.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 998 KB

english, 2000

32

Insulin and Insulin-like growth factor-1 can activate the phosphoinositide-3-kinase /Akt/FoxO1 pathway in T cells in vitro

Mirdamadi, Yasaman, Bommhardt, Ursula, Goihl, Alexander, Guttek, Karina, Zouboulis, Christos C., Quist, Sven, Gollnick, Harald

Journal:

Dermato-Endocrinology

Year:

2017

Language:

english

File:

PDF, 2.02 MB

english, 2017

33

Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness

Lowinus, Theresa, Bose, Tanima, Busse, Stefan, Busse, Mandy, Reinhold, Dirk, Schraven, Burkhart, Bommhardt, Ursula H.H.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.32 MB

english, 2016

34

Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy

Bommhardt,, Schraven,, Simeoni,

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 821 KB

english, 2019

35

Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy

Bommhardt,, Schraven,, Simeoni,

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 821 KB

2019

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